Aswathy was born as the daughter of Mr. Shivan Manoharan and Mrs Anitha at Karappuzha, Kottayam, Kerala. Her father worked as a civil engineer. Her sister is settled in USA. Aswathy completed 10th std from Girideepam Bethany school Kottayam and higher secondary education at Excelsior school Kottayam.
Being a classical and contemporary dancer, she began her Bharatanatyam training at the age of six. Aswathy is a yoga instructor at Aayana Yoga Academy, Bangalore. She is also trained in contemporary dance, yoga and kalaripayattu.
Aswathy Manoharan started her career in acting with the film ‘Swathantryam Ardharathriyil’ directed by Tinu Pappachan. She played the character of Betty in the thriller which boasts of few high-voltage action scenes. Betty, the wife of Jacob (Antony Varghese) is an orphan, introvert and soft-spoken.