Yazir was born as the eldest son of Mr. C R Saleem and Mrs. Ramlaat Aluva, Ernakulam, Kerala. He has two brothers and two sisters. He completed his Bachelor of Technology in electronics and communication from KMEA Engineering College, Edathala.
Yazir Saleem started his career as an assistant director in the film ‘Ivan Maryadaraman’. He made his silver screen debut as an actor with the film ‘Happy Journey’ directed by Boban Samuel. He played a supporting role as Hussain in the film ‘Acha Din’.
Yazir entered the tamil film industry with the film ‘Moondru Rasikarkal, playing one among the three hardcore Vijay fans. He essayed the pivotal role of Devan in the thriller ‘Ore Mukham’ set against the backdrop of a campus in 1980’s. He also acted in the film ‘Kasaba’.